Click here for the Pharmacology Home Page Click here for the UC Irvine Home Page Click here for the School of Medicine Home Page

Candice A. Gellner

Entered program Fall 2013
Advisor: Frances M. Leslie, Ph.D.
Candice is a Graduate Student Researcher in Dr. Leslie's lab and can be reached at


2013 - present
PhD in Pharmacology & Toxicology, in progress
University of California, Irvine

August 2006-May 2012
B.S. in Biochemistry
California State University, Sacramento

Research Experience

Spring 2013 - present
Understanding how the non-nicotine constituents affect models of tobacco dependence. Research Adviser: Dr. Frances Leslie
Department of Pharmacology, University of California, Irvine, School of Medicine

Winter 2012
Investigating liposomes as targeted drug delivery systems. Research Adviser: Dr. Young Jik Kwon
Department of Pharmaceutical Sciences, University of California, Irvine

Fall 2012
Warfarin inhibition of M. tuberculosis DsbG when complexed with M. tuberculosis VKOR. Research Adviser: Dr. Celia Goulding
Department of Molecular Biology and Biochemistry, University of California, Irvine

Summer 2011
Investigation of different truncations of Apolipoproteins and their use in NLPs. Research Advisor: Dr. Matthew Coleman
Lawrence Livermore National Laboratory

The use of nanolipoproteins (NLPs) to study over expressed proteins in breast cancer. Research Adviser: Dr. Paul Henderson
Department of Internal Medicine, Hematology and Oncology, University of California, Davis

Investigation, isolation, and characterization of cross-linking L178H ApoA1. Research Adviser: Dr. Linda Roberts
Department of Chemistry, California State University, Sacramento

Investigation of microdosing as a form of cancer treatment Investigation of the use of micelles as a drug delivery platform Using NLPs to study breast cancer. Research Advisor: Dr. Paul Henderson
Center for Biophotonics Science and Technology, University of California, Davis

Research Interests

  • Understanding how nicotine and other drugs of abuse affect the developing brain.
  • Understanding lung cancer and the influence of smoking.
  • The use of delivery platforms in cancer therapy.
  • Designing drugs to be used in delivery platforms for disease therapies.
  • Influences of cancer stem cells.
  • X-ray crystallography and the biological properties of potential drug targets.

Honors and Awards

  • Undergraduate Poster Presentation Award

            SACNAS National Conference                                                 October 2011

  • 2011 Partnerships for Innovation Commercialization Plan Award

            Accelerated Medical Diagnostics (AMD)                                    May 2011

  • Best Presentation Award

            Center for Biophotonics Science and Technology (CBST)            June 2010 – Sept. 2010



  • He, W., Scharadin, T.M., Saldana, M., Gellner, C., et al. (2015) Cell-free expression of functional receptor tyrosine kinases. Sci. Rep. 5. doi:10.1038/srep12896

 In preparation:

  • Gellner, C., Belluzzi, J., and Leslie F.M. Age Differences in Self-Administration of Nicotine and Cigarette Smoke Extract.

Conference Presentations/Abstracts

  • “Self-administration of cigarette smoke extract vs. nicotine alone in adolescent and adult male rats”

           Poster presented at Society for Neuroscience, Walter E. Washington Convention Center,Washington, DC(2014)

  •  “Concentration dependence of cross-linking L178H apolipoprotein A-I”

           Poster presented at ACS Undergraduate Symposium, Mills College, Oakland, CA (2012) 

  •   “Obtaining access to membrane proteins using cell-free technologies and nanolipoproteins”

           Poster presented at SACNAS National Conference, San Jose, CA (2011)

  • “Obtaining access to membrane proteins using cell-free technologies and nanolipoproteins”

           Scientific abstract and presentation, CBST Summer Internship Program, Davis, CA (2011) 

  • “Ex Vivo Synthesis of ErbB2/Her2 NLPs for Biochemical, Structural and Drug Development Studies”                                                                                                                                 

           Scientific abstract and presentation, CBST Summer Internship Program, Sacramento, CA (2010)


  • Society for Neuroscience