Click here for the Pharmacology Home Page Click here for the UC Irvine Home Page Click here for the School of Medicine Home Page


UC Irvine Department of Pharmacology faculty members are doing cutting-edge research in several areas. Investigators, and their areas of study, include:

In Vivo Pharmacology »

In Vivo Pharmacology studies the action of drugs on the whole animal. Researchers study the effect of drugs on a wide range of behaviors and physiological endpoints including, feeding, locomotion, learning and memory, reward, seizures, sleep, stress, stroke and anti-aging.


Cardiovascular Pharmacology »

Cardiovascular Pharmacology studies the heart, vascular system and parts of the nervous and endocrine systems that regulate cardiovascular function. Researchers observe the effects of drugs on arterial pressure, blood flow in specific vascular beds, release of physiological mediators and neural activity in central nervous system structures.


Drug Abuse »

Drug Abuse research in pharmacology seeks to offer help in suppressing withdrawal and in reducing drug craving by blocking the effects of drugs on the pleasure centers of the brain. Researchers study the physical and behavioral processes of addiction to drugs such as nicotine, marijuana and heroin.


Hormonal Actions »

Hormonal Actions research involves the study of hormones or hormone derivatives, or drugs that alter the effects of naturally occurring hormones. Endocrine pharmacologists study the origins and action of metabolic diseases.


Neuropharmacology »

Neuropharmacology studies encompass the nervous system, including the brain, spinal cord and nerves that communicate with all parts of the body. Researchers study drug actions of specific diseases of the nervous system and use drugs as tools to understand basic mechanisms of neural function.


Novel Therapies »

Novel Therapies research involves the study of new drugs or therapeutic processes, or new uses for existing drugs and therapies, to treat illness. Researchers evaluate the medical usefulness of a potential drug by identifying the specific manner in which it disrupts the disease process.


Signal Transduction »

Signal Transduction involves the study of gene regulation to explore the body's responses, at the cellular level, to changes in the environment, the use of signaling pathways to regulate the expression of genes and the role of gene expression in human disease. Researchers identify the genes and mechanisms involved, including cellular and molecular biology of transcription, chromatin remodeling and epigenetics - specifically within physiological settings - and they work to discover and refine new inhibitors or activators.